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04 八月 2021

On-DNA Derivatization of Quinoxalin-2-ones by Visible-Light-Triggered Alkylation with Carboxylic Acids

Bioconjug Chem:On-DNA Derivatization of Quinoxalin-2-ones by Visible-Light-Triggered Alkylation with https://doi.org/10.1021/acs.bioconjchem.1c00346
11 五月 2021

Toward the assembly and characterization of an encoded library hit confirmation platform: Bead-Assisted Ligand Isolation Mass Spectrometry (BALI-MS)

Bioorg. Med. Chem. 41 (2021) 116205 https://10.1016/j.bmc.2021.116205
10 五月 2021

DEL兼容反应类型拓展-可见光催化芳香叔胺碳氢活化碳碳键构筑反应

Org. Lett., 2021, 23 (9), 3486-3490 https://doi.org/10.1021/acs.orglett.1c00924
14 四月 2021

成都先导与MSD合作开发出适用于DNA编码化合物库合成的卤代芳烃甲酸化反应

Bio. Med. Chem. 2021 https://doi.org/10.1016/j.bmc.2021.116118
30 三月 2021

Development and Validation of High-Content Analysis for Screening HDAC6-Selective Inhibitors

SLAS Discov：Development and Validation of High-Content Analysis for Screening HDAC6-Selective Inhibi https://10.1177/24725552211002463
15 三月 2021

成都先导开发出适用于DNA编码化合物库合成的碳-硫键偶联反应

Bioconjugate Chem. 2021 https://doi.org/10.1021/acs.bioconjchem.1c00076
09 三月 2021

成都先导与强生合作共同开发出基于胆固醇修饰的DNA内标的DEL化学反应监测方法

Bioconjugate Chem. 2021 https://doi.org/10.1021/acs.bioconjchem.1c00045
11 二月 2021

Employing Photocatalysis for the Design and Preparation of DNA‐Encoded Libraries: A Case Study

Chem. Rec. 2021, 21, 616 https://doi.org/10.1002/tcr.202000148
28 一月 2021

优化IMQ模型为IL17通路拮抗剂药物研发助力

BMC Immunol . 2021 Jan 28;22(1):11 10.1186/s12865-021-00401-3
08 一月 2021

Selecting Approaches for Hit Identification and Increasing Options by Building the Efficient Discovery of Actionable Chemical Matter from DNA-Encoded Libraries

DISCOVERY: Advancing the Science of Drug Discovery, vol. 26, no. 2, Feb. 2021, pp. 263–280 https://doi.org/10.1177/2472555220979589

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